Pyrroloquinoline Quinone (PQQ)
A potent redox-active cofactor and neuroprotective agent known for its unique ability to stimulate mitochondrial biogenesis and optimize cellular energy output.
Mitochondrial Biogenesis & Growth
PQQ is one of the few compounds capable of activating PGC-1α, a master regulator that triggers the birth of new mitochondria within aging cells. This process increases the density of cellular power plants, leading to enhanced ATP production and vitality.
Cognitive & NGF Support
PQQ promotes the synthesis of Nerve Growth Factor (NGF), crucial for the repair and maintenance of healthy neurons. Clinical evidence suggest it helps improve memory, attention, and executive function by reducing neuroinflammation.
Super-Antioxidant Activity
PQQ is exceptionally stable and can carry out thousands of antioxidant cycles without being destroyed. It works synergistically with CoQ10 to protect cells from oxidative stress and maintain cardiovascular integrity.
References
Rucker, R., et al. (2009). "Potential physiological importance of pyrroloquinoline quinone." Alternative Medicine Review, 14(3), 268-77.
Nakano, M., et al. (2012). "Effect of Pyrroloquinoline Quinone (PQQ) on Mental Status of Middle-Aged and Elderly Persons." FOOD Style 21, 13(7), 50-53.
Harris, C. B., et al. (2013). "Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects." Journal of Nutritional Biochemistry, 24(12), 2076-2084.